Overview
LEADING THE DISCOVERY
of Allosteric Binding Sites to Create New Medicines
Gain Therapeutics is redefining drug discovery with its SEE-Tx™ target identification platform.
By identifying and optimizing allosteric binding sites that have never before been targeted, Gain is unlocking new treatment options for difficult-to-treat disorders characterized by protein misfolding, including lysosomal storage disorders.
Protein misfolding is an underlying biological issue of many diseases, including lysosomal storage disorders and some neurodegenerative diseases such as Parkinson’s disease. When a protein misfolds, its 3D structure is disrupted and it can no longer function properly. While some treatments are available for these types of disorders, they have significant limitations.
Gain was originally established in 2017 with the support of its founders and institutional investors such as TiVenture, 3B Future Health Fund (previously known as Helsinn Investment Fund) and VitaTech. It has been awarded funding support from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) and The Silverstein Foundation for Parkinson’s with GBA, as well as from the Eurostars-2 joint program with co-funding from the European Union Horizon 2020 research and Innosuisse. In July 2020, Gain Therapeutics, Inc. completed a share exchange with Gain Therapeutics SA, a Swiss corporation, whereby GT Gain Therapeutics SA became a wholly owned subsidiary of Gain Therapeutics, Inc.
Leadership Team
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Matthias Alder Chief Executive Officer |
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Manolo Bellotto, Ph.D. Chief Strategy Officer and General Manager |
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Salvatore Calabrese Chief Financial Officer |
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Xavier Barril, Ph.D. Chief Technology Officer |
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Ana Maria Garcia-Collazo, Ph.D. VP Research & Site Leader |
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Elena Cubero-Jorda, Ph.D. Director Computational Chemistry |
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Natália Pérez-Carmona, Ph.D. Director Biology |
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Terenzio Ignoni, Pharm.D. SVP Technical Operations |
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Dr. Joanne Taylor SVP, Research |
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Board of Directors
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Khalid Islam, Ph.D. Chairman |
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Matthias Alder CEO |
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Eric I. Richman Independent Member |
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Jeffrey Riley Independent Member |
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Dov Goldstein, M.D. Independent Member |
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Gwen Melincoff Independent Member |
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Claude Nicaise, M.D. Independent Member |
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Hans Peter Hasler Independent Member |
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Partners |
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Grants |
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Patient Associations |
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Centers of Research, Translational Science & Clinical Excellence |
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Interested in working with a dynamic team of research, |